Rye DB, Bliwise DL, Parker K, Trotti LM, Saini P, Fairley J, Freeman A, Garcia PS, Owens MJ, Ritchie JC, Jenkins A; Bliwise; Parker; Trotti; Saini; Fairley; Freeman; Garcia; Owens; Ritchie; Jenkins 21 November 2012 | Psychology Today, On-line blog, 25 March• Miyagawa T, Miyadera H, Tanaka S, Kawashima M, Shimada M, Honda Y, Tokunaga K, Honda M; Miyadera; Tanaka; Kawashima; Shimada; Honda; Tokunaga; Honda 2011 |
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"Selegeline hydrochloride treatment in narcolepsy | "Autoimmunity: A new clue to sleepiness" |
The VLPO neurons inhibit and are inhibited by the TMN histamine neurons and REM-off monoamine neurons.
3Orexin neurons, located in the lateral and posterior hypothalamus and excite monoaminergic neurons during wakefulness and cholinergic neurons during REM sleep | Hence, one hypothesis is that because of the small number of these neurons in narcolepsy there is less excitation of the monoaminergic neurons during wakefulness and consequently a tendency for the cholinergic neurons to escape from the monoaminergic inhibition resulting in sudden attacks of atonia and REM periods |
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Emory University - Georgia Research Alliance | Manni, R; Politini, L; Nobili, L; Ferrillo, F; Livieri, C; Veneselli, E; Biancheri, R; Martinetti, M; Tartara, A May 2001 |
Emory University - Georgia Research Alliance | Biological rhythms, sleep, and hypnosis |
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"EIF3G is associated with narcolepsy across ethnicities" | Orexin neurons, located in the lateral and posterior hypothalamus and excite monoaminergic neurons during wakefulness and cholinergic neurons during REM sleep |