The most common adverse effects are diarrhoea, skin rash and headache which are mild and transient | - Helicobacter Pylori associated with peptic ulcer disease : 40 - 80 mg daily with Amoxicillin 1 |
---|---|
The rare adverse effects include arthralgia, myalgia and blood disturbances | - It may increase absorption of Digoxin and decrease the effectiveness of Prednisone |
It is almost completely metabolized in the liver and rapidly eliminated mostly in the urine | Maintenance therapy : 20 mg once daily |
---|---|
- Omeprazole inhibits the activity of some hepatic cytochrome P- 450 enzymes | - Duodenal ulcer : 20 mg once daily for 4 weeks |
Precautions Treatment with Omeprazole may mask symptoms of malignancy and therefore delay diagnosis.
23Use in pregnancy and lactation It is not recommended unless prescribed by the physician | DRUG INTERACTIONS : - Omeprazole can prolong the elimination of Diazepam , Warfarin and Phenytoin |
---|---|
5 gm daily in divided doses for 2 weeks | RESTRICTIONS ON USE : Contraindications Hypersensitivity to Omeprazole |
Strip is indicated in the treatment of : - Gastro-oesophageal reflux disease.
2